实用医学杂志 ›› 2021, Vol. 37 ›› Issue (9): 1222-1226.doi: 10.3969/j.issn.1006⁃5725.2021.09.026

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PM2.5对男性生殖系统的影响研究进展

赵银银, 邱娴娴,肖跃海, 江克华, 罗大金, 孙发   

  1. 1 贵州医科大学(贵阳550004);2 贵州省人民医院(贵阳550002)

  • 出版日期:2021-05-10 发布日期:2021-05-10
  • 通讯作者: 孙发 E⁃mail:sfguizhou@163.com

Research progress of the influence of PM2.5 on male reproductive system

ZHAO Yinyin,QIU Xianxian, XIAO Yuehai,JIANG Kehua,LUO Dajin,SUN Fa.    

  1. Guizhou Medical UniversityGuiyang 550004China;*Gui⁃ zhou Provincial People′s HospitalGuiyang 550002China 
  • Online:2021-05-10 Published:2021-05-10
  • Contact: SUN Fa E⁃mail:sfguizhou@163.com

摘要:

环境细颗粒物(PM2.5)是一种大气污染物,是对公众健康的主要可预防威胁之一,是全球公认对人体健康有不利影响的物质,也是全球公共卫生面临的一个巨大问题。近年来,空气污染问题日趋严重,多项研究表明大气污染物对人类的身体健康产生了不利影响,包括心、肺、睾丸等多功能多器官损害。研究表明微粒物质(PM)是男性精液质量恶化的一个危险因素,而 PM2.5 作为大气污染物的一种,对于精子质量、基因、染色体、激素等的损害作用,逐渐被各研究学者所注意,并开始探究 PM2.5 对男性生殖系统的损伤作用及机制,但目前其作用机制尚不完全清楚。本文就近年来 PM2.5 损伤男性生殖系统的研究进展进行总结。

关键词:

PM2.5, 男性生殖系统, 精子, 机制, 雄性激素

Abstract:

Environmental fine particulate matter(PM2.5),an air pollutant,is one of the major prevent⁃ able threats to public health. It is a globally recognized substance with adverse effects on human health and has become a huge problem for global public health. In recent years,the problem of air pollution had become increas⁃ ingly serious. A number of studies have showed that air pollutants exert adverse effects on human health,including damage to the heart,lungs,testicles and other multifunctional organs. Studies also showed that PM is a risk factor for male semen quality deterioration. As a kind of atmospheric pollutants,PM2.5 affects male sperm quality genes,chromosomes and hormones. It was gradually explored by researchers and they began to explore PM2.5 on male reproductive system function and mechanism of injury. However,its mechanism is not fully clear. This paper summarized the research progress about the damage of PM2.5 to male reproduction system in recent years. 

Key words:

PM2.5, male reproductive system, sperm, mechanism, androgens