实用医学杂志 ›› 2021, Vol. 37 ›› Issue (9): 1155-1163.doi: 10.3969/j.issn.1006⁃5725.2021.09.012

• 临床研究 • 上一篇    下一篇

声诱发反应在妊娠期高血压胎儿听力监测中的应用

郭丽芳, 陈丽文, 郑雅萍, 曾笑梅, 陈洵艳   

  1. 宁德师范学院附属宁德市医院1 妇产科,2 耳鼻咽喉科(福建宁德 352100);宁德市耳鼻咽喉科研究所(福建 宁德 352100)

  • 出版日期:2021-05-10 发布日期:2021-05-10
  • 通讯作者: 陈洵艳 E⁃mail:1324412807@qq.com;曾笑梅 E⁃mail:673416104@qq.com
  • 基金资助:
    福建省宁德市科技局科研计划资助项目(编号:20170065)


Effect of acoustic stimulation test in monitoring of fetal hearing with HDP 

GUO Lifang,CHEN Liwen, ZHENG Yaping,ZENG Xiaomei,CHEN Xunyan   

  1. Department of Gynaecology and Obstetrics,Fujian Medical Uni⁃ versity Ningde Hospital,Ningde 352100,China 

  • Online:2021-05-10 Published:2021-05-10
  • Contact: CHEN Xunyan E⁃mail:1324412807@qq. com;ZENG Xiaomei E⁃mail:673416104@qq. com

摘要:

目的 探讨声诱发反应(acoustic stimulation test,AST)在妊娠期高血压(hypertensive disor⁃ ders of pregnancy,HDP)胎儿听力监测中的可行性。方法 选取 HDP 孕妇,根据严重程度分为轻度组和重度组,再据胎龄分成足月组和早产组。所有孕妇行 AST,出生后的围产儿行听力筛查与诊断。随机选取同期无 HDP 孕妇形成对照组,将各组 AST 和听力结果对比。结果 重度 HDP 组患儿 AST 阳性率明显低于 轻度 HDP 组和无 HDP 组;在 AST 阴性中,重度 HDP 患儿听力损失率明显高于轻度 HDP 组和无 HDP 组;在AST 阳性中,患儿听力损失多为轻、中度,而 AST 阴性中,无 HDP 者听力损失多为双耳中、重度,HDP 者听力损失则多为单耳或/和双耳中、重度。结论 AST 能够预估和监测胎儿听力情况,可供临床选择使用;尤其重度HDP 组AST 阴性者,听力损失率较高,应加强监测和复查。

关键词:

声诱发反应, 妊娠期高血压, 听力筛查

Abstract:

Objective To explore the feasibility of acoustic stimulation test(AST)in monitoring of fetal hearing with hypertensive disorders of pregnancy(HDP). Methods The pregnant women with HDP were divided into mild group and severe group according to the severity of HDP,and then into full ⁃term group and premature group according to gestational age. ASTs were performed for all subjects,and those neonatal hearing were screened and diagnosed. The pregnant women without HDP hospitalized during the same period were randomly selected as the control group. The comparisons were done among the groups in terms of AST and hearing results. Results The positive rates of the AST in the severe HDP group was significantly lower than that in the mild HDP group and non⁃ HDP. The hearing loss rate of the severe HDP group was significantly higher than that of the mild HDP group and non⁃HDP group in the negative AST. The majority of hearing loss was mild to moderate in the positive AST,while the hearing loss of the non⁃HDP group was moderate to severe in both ears,and the majority of the loss in the HDP group was mostly in a single ear or/and both ears,from moderate or severe in the negative AST. Conclusion The AST is effective and feasible for the prediction and monitoring of the fetal hearing. The rate of hearing loss is higher in severe HDP with negative AST ,and the emphasis should be put on strengthening hearing monitoring and rescreening. 

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