PPDO双向锯齿线倒V型布线法与直线型布线法用于改善鼻唇沟皱纹的临床疗效

doi:10.3969/j.issn.1006-5725.2025.12.012

摘要/Abstract

摘要：

目的基于面部年轻化和鼻唇沟皱纹的改善，评估聚对二氧环己酮（PPDO）双向锯齿线倒V型布线法与直线型布线法用于改善鼻唇沟皱纹的临床疗效分析。方法选取2023年3月至2024年1月，60例因鼻唇沟皱纹至蚌埠医科大学第一附属医院整形外科行PPDO皮下埋植提升术的求美者，随机分为观察组和对照组，根据其面部松垂特点和程度设计埋线数量和分布，观察组予以倒V型布线提升，对照组予以传统的直线型布线提升。分别于术后4、12、24周随访并统计临床疗效、面部整体改善情况、记录并发症评估手术安全性以及满意度调查。结果术后两组患者各个时间段的皱纹严重程度评定量表（WSRS）评分较术前均有所下降，差异具有统计学意义（P < 0.05）；两组患者术后各对应时间点的WSRS均为观察组低于对照组，差异具有统计学意义（P < 0.05）；两组患者均为术后12周时WSRS评分最低，术后24周评分虽较术后12周有所增加，差异具有统计学意义（P < 0.05）；观察组面部整体改善的有效率为93.33%，明显高于对照组的73.33%，差异有统计学意义（χ² = 4.320，P <0.05）；两组均无明显并发症发生；观察组患者满意度为4.067 ± 0.828，显著高于对照组3.400 ± 0.932，差异有统计学意义（t = 2.929，P < 0.05）。结论 PPDO双向锯齿线倒V型布线法与直线型布线法均能较好地改善鼻唇沟皱纹；倒V型布线法相较于直线型布线法的提升效果更显著，受试者满意度高，耗材更少；两种布线方式均在术后第12周达到最佳效果；两种手术方式均无明显并发症发生。

关键词: PPDO双向锯齿线, 鼻唇沟, 倒V型布线法, 直线型布线法, 面部年轻化

Abstract:

Objective To assess the clinical effectiveness of Poly（p-dioxanone）（PPDO） bidirectional sawtooth inverted V-shaped wiring and straight wiring in ameliorating nasolabial fold wrinkles within the context of facial rejuvenation. Methods Between March 2023 and January 2024， 60 patients presenting with nasolabial fold wrinkles who underwent PPDO subcutaneous implantation and lifting in the Department of Plastic Surgery at the First Affiliated Hospital of Bengbu Medical University were randomly allocated into an observation group and a control group. At 4 weeks， 12 weeks， and 24 weeks post-surgery， the clinical efficacy was statistically analyzed. The incidence of complications was documented to evaluate the safety of the procedure， and a satisfaction survey was carried out. Results In each time period， the Wrinkle Severity Rating Scale （WSRS） scores of both groups decreased significantly when compared to those prior to the operation （P < 0.05）. At each corresponding time point after surgery， there was a statistically significant difference in the WSRS scores between the two groups in the observation group （P < 0.05）. In both groups， the WSRS score was the lowest at 12 weeks post-surgery， and the score at 24 weeks post-surgery was significantly higher than that at 12 weeks post-surgery （P < 0.05）. The overall effective rate of facial improvement in the observation group was 93.33%， which was significantly higher than that in the control group （73.33%）. The difference was statistically significant （χ² = 4.320， P < 0.05）. No obvious complications occurred in either group. The satisfaction rate in the observation group was 4.067 ± 0.828， which was significantly higher than that in the control group （3.400 ± 0.932）. The difference was statistically significant （t = 2.929， P < 0.05）. Conclusions Both the PPDO two-way sawtooth line inverted V-shaped wiring method and the straight wiring method can effectively improve nasolabial fold wrinkles. Compared with the straight wiring method， the inverted V wiring method demonstrates a more pronounced improvement effect， higher subject satisfaction， and fewer consumables. The optimal results were achieved at 12 weeks after surgery for both wiring methods. Moreover， neither surgical procedure was associated with significant complications.

Key words: PPDO bidirectional zigzag line, nasolabial folds, inverted V wiring, straight wiring method, facial rejuvenation

中图分类号:

R622

李渺,王怀谷,蒋邦红,程曙,孙理想. PPDO双向锯齿线倒V型布线法与直线型布线法用于改善鼻唇沟皱纹的临床疗效[J]. 实用医学杂志, 2025, 41(12): 1853-1858.

Miao LI,Huaigu WANG,Banghong JIANG,Shu CHENG,Lixiang SUN. PPDO bidirectional sawtooth line inverted V⁃shaped wiring method and straight wiring method are used to improve the clinical efficacy of nasolabial fold wrinkles[J]. The Journal of Practical Medicine, 2025, 41(12): 1853-1858.

图/表 7

图1

图 2

表1

表 2

表3

图3

图 4

参考文献 20

1	翟培明，方卫婷，王了然，等. 鼻唇沟区域应用线雕的解剖学基础和临床策略［J］. 中国美容医学，2022，31（9）：203-205.
2	SARIGUL GUDUK S， CEVIK CENKERI H， DERIN CICEK E， et al. Evaluation of aging changes of the superficial fat compartments of the midface over time： A computed tomography study［J］. J Cosmet Dermatol， 2022， 21（4）： 1430-1435. doi:10.1111/jocd.14292 doi: 10.1111/jocd.14292
3	SPATARO E A， DIERKS K， CARNIOL P J. Microneedling-associated procedures to enhance facial rejuvenation［J］. Facial Plast Surg Clin North Am， 2022， 30（3）： 389-397. doi:10.1016/j.fsc.2022.03.012 doi: 10.1016/j.fsc.2022.03.012
4	WEI B， DUAN R， XIE F， et al. Advances in face-lift surgical techniques： 2016-2021［J］. Aesthetic Plast Surg， 2023， 47（2）： 622-630. doi:10.1007/s00266-022-03017-z doi: 10.1007/s00266-022-03017-z
5	HONG G W， HU H， PARK S Y， et al. What are the factors that enable thread lifting to last longer？［J］. Cosmetics， 2024， 11（2）： 42. doi:10.3390/cosmetics11020042 doi: 10.3390/cosmetics11020042
6	HONG G W， KIM S B， PARK S Y， et al. SMAS repositioning technique utilizing cog thread： Anatomical perspectives［J］. Skin Res Technol， 2024， 30（3）： e13650. doi:10.1111/srt.13650 doi: 10.1111/srt.13650
7	WANG Y， YIN B， LI F. Facial rejuvenation and contouring with radiofrequency-assisted procedures in Asians［J］. Clin Plast Surg， 2023， 50（1）： 43-49. doi:10.1016/j.cps.2022.08.009 doi: 10.1016/j.cps.2022.08.009
8	KOCHHAR A， KUMAR P， KARIMI K. Minimally invasive techniques for facial rejuvenation utilizing Polydioxanone Threads［J］. Clin Plast Surg， 2023， 50（3）： 465-477. doi:10.1016/j.cps.2022.12.011 doi: 10.1016/j.cps.2022.12.011
9	安靖雯，冯俊云，饶磊，等. 细胞衰老与瘢痕纤维化的关系研究进展［J］. 实用医学杂志，2024，40（12）：1749-1754.
10	LONG T， ZARRAGA M， AGUILERA S B. Nodules on the anterior neck following poly-l-lactic acid injection［J］. Cutis， 2022， 109（6）： E15-E17. doi:10.12788/cutis.0555 doi: 10.12788/cutis.0555
11	ZHUKOVA O， DYDYKIN S， KUBÍKOVÁ E， et al. A new complex minimally invasive thread lift method for one-time three-step fixation of the face and neck soft tissues［J］. Arch Plast Surg， 2022， 49（3）： 296-303. doi:10.1055/s-0042-1748641 doi: 10.1055/s-0042-1748641
12	蒙根，贾麒钰，曙格拉·拜布提，等. 中面部除皱术的解剖与术式演变及并发症的研究进展［J］. 中国美容医学， 2024， 33 （2）： 186-190.
13	王硕，王怀谷，蒋邦红，等. 硅凝胶联合1565 nm非剥脱点阵激光在面部急诊外伤后瘢痕治疗中的疗效观察［J］. 实用医学杂志，2023，39（19）：2511-2516. doi:10.3969/j.issn.1006-5725.2023.19.017 doi: 10.3969/j.issn.1006-5725.2023.19.017
14	SULAMANIDZE M A， SHIFFMAN M A， PAIKIDZE T G， et al. Facial lifting with APTOS threads［J］. Int J Cosmet Surg Aesthet Dermatol， 2001， 3（4）： 275-281. doi:10.1089/15308200152941199 doi: 10.1089/15308200152941199
15	GOEL A， RAI K. Non‐surgical facelift-by PDO threads and dermal filler： A case report［J］. J Cosmet Dermatol， 2022， 21（10）： 4241-4244. doi:10.1111/jocd.14921 doi: 10.1111/jocd.14921
16	IRANMANESH B， KHALILI M， MOHAMMADI S， et al. Employing microbotox technique for facial rejuvenation and face‐lift［J］. J Cosmet Dermatol， 2022， 21（10）： 4160-4170. doi:10.1111/jocd.14768 doi: 10.1111/jocd.14768
17	HONG G W， PARK S Y， YI K H. Revolutionizing thread lifting： Evolution and techniques in facial rejuvenation［J］. J Cosmet Dermatol， 2024， 23（8）： 2537-2542. doi:10.1111/jocd.16326 doi: 10.1111/jocd.16326
18	KHAN G， KIM B J， KIM D G， et al. Retrospective study of the absorbable braided polydioxanone threads′ usefulness in the aged lower eyelids' rejuvenation［J］. J Cosmet Dermatol， 2022， 21（11）： 5952-5956. doi:10.1111/jocd.15257 doi: 10.1111/jocd.15257
19	王炜，马树林，付莉. 不同术式在中下面部除皱术中的应用及美学效果对比［J］. 中国美容医学，2023，32（3）：62-65.
20	KHAN G， AHN K H， KIM S Y， et al. Combined press cog type and cog PDO threads in comparison with the cog PDO threads in facial rejuvenation［J］. J Cosmet Dermatol， 2021， 20（10）： 3294-3298. doi:10.1111/jocd.14092 doi: 10.1111/jocd.14092

项目	观察组（n = 30）	对照组（n = 30）
术前与术后4周	P < 0.001	P < 0.001
术前与术后12周	P < 0.001	P < 0.001
术前与术后24周	P < 0.001	P < 0.001
术后4周与术后12周	0.448	P < 0.001
术后12周与术后24周	P < 0.001	P < 0.001

组别	例数	术前	术后4周	术后12周	术后24周
观察组	30	6.90 ± 0.96	4.53 ± 1.167	4.43 ± 1.382	4.90 ± 1.062
对照组	30	6.63 ± 0.928	5.53 ± 1.042	5.10 ± 1.094	5.90 ± 1.125
t值		1.094	-3.502	-2.072	-3.541
P值		0.278	0.001	0.043	0.001

组别	非常明显改善	明显改善	一定程度改善	无变化	更差	有效率/%
观察组	5	13	10	2	0	93.33
对照组	2	8	12	8	0	73.33
χ² 值	4.320
P值	0.038

[1]	秦傲霜,杨晨,崔鑫,马戈甲,郭小伟,周煦川,刘宾. 透明质酸支架联合脂肪干细胞促进下肢慢性创面愈合的研究[J]. 实用医学杂志, 2025, 41(7): 991-996.
[2]	陈盈盈,郭治宏,刘德伍. 血管基质片段在整形外科领域中的应用研究进展[J]. 实用医学杂志, 2025, 41(3): 442-446.
[3]	王梦霄,陈志勇,罗涵,张光钢. 改良CO₂点阵激光联合光动力对难愈性创面的疗效[J]. 实用医学杂志, 2025, 41(1): 53-59.
[4]	李亮,黄家俊,顾立强. 利用臂丛残根作为动力源神经修复上干的随访分析[J]. 实用医学杂志, 2024, 40(24): 3489-3496.