实用医学杂志 ›› 2021, Vol. 37 ›› Issue (2): 134-137.doi: 10.3969/j.issn.1006⁃5725.2021.02.002

• 专题报道 • 上一篇    下一篇

肌少症对老年骨质疏松性胸腰段脊柱压缩性骨折术后病死率的影响

王华, 王超, 殷建
  

  1. 南京医科大学附属江宁医院骨科(南京 211100)

  • 出版日期:2021-01-25 发布日期:2021-01-25
  • 通讯作者: 殷建 E⁃mail:yinjiandoc@163.com
  • 基金资助:

    国家自然科学基金(编号:81802198);江苏省自然 科学基金(编号:SBK2019022658);南京医科大学康达学院科研 发展基金(编号:KD2019KYJJZD021)

Effect of sarcopenia on postoperative mortality of elderly patients suffering osteoporotic thoracolumbar compression fracture

WANG Hua,WANG Chao,YIN Jian
  

  1. Department of Orthopedics,the Affiliated Jiangning Hospital with Nanjing Medical University,Nanjing 211100,China
  • Online:2021-01-25 Published:2021-01-25
  • Contact: YIN Jian E⁃mail:yinjiandoc@163.com

摘要:

目的 探讨肌少症对老年患者骨质疏松性胸腰段脊柱压缩性骨折(osteoporotic thoracolum⁃ bar compression fracture,OTLCF)术后病死率的影响。方法 20142月至20172月,共114OTLCF患者纳入本研究。根据 SMI 诊断界值分为肌少症组及非肌少症组。采用Kaplan Meier分析两组患者的生存曲线,卡方检验对比两组在术后12、24、36个月生存率差异,Cox 比例风险模型单因素分析肌少症、骨折部位、年龄、性别及美国麻醉医师协会(ASA)等级等多变量因素对OTLCF术后病死率的影响。结果 组术后 36 个月病死率差异有统计学意义(P = 0.016)。患有肌少症及ASA 等级较高的患者,术后36个月病死率较高。结论 合并肌少症会增加OTLCF 患者术后远期(36 个月)死亡的风险。ASA 等级较高的患 者术后远期死亡风险较高。

关键词:

Abstract:

Objective To investigate the effect of sarcopenia on mortality after osteoporotic thoracolumbar compression fracture(OTLCF)in elderly patients. Methods A total of 114 elderly patients who met the inclusion and exclusion criteria were included from February 2014 to February 2017. The patients were divided into sarcope⁃ nia group and non⁃sarcopenia group according to the SMI diagnosis cut⁃off value. Kaplan Meier was used to analyze the survival curves of the two groups of patients,and the chi⁃square test to compare the survival rate between the two groups 12,24 and 36 months after the surgery. The Cox proportional hazards model was used to analyze the effects of multivariate factors such as sarcopenia,thoracic or lumbar fractures,age,gender,and American Society of Anesthetists(ASA)grade on postoperative mortality of OTLCF. Results There was statistical difference between the 36⁃month mortality rates(P = 0.016). Patients with sarcopenia and patients with higher ASA grade had a higher mortality rate 36 months after the surgery. Conclusion Sarcopenia increases the risk of long ⁃term(36 months

Key words: