关键词:

子宫内膜异位症, 凝血, 血栓弹力图, 卵巢良性肿瘤

Abstract:

Objective To investigate the correlation between thromboelastograph andendometriosis and its clinical predictive value. Methods A total of 316 patients diagnosed with endometriosis were included in the endometriosis group，and 131 cases of patients diagnosed with other benign ovarian tumors were selected as the control group. The predictive value of the occurrence and development of endometriosis and the correlation of various clinicopathological parameters were evaluated. Results Compared with the control group，the R value and K value of patients in the endometriosis group were decreased，while α Angle，MA value and CI value were increased，the differences were statistically significant（P < 0.05），and R value，α Angle and MA value were independent influ⁃ encing factors for the occurrence of endometriosis（P < 0.01）. The AUC of α Angle was 0.706. The AUC of MA value was 0.730. With the increase of ASRM stage，α Angle and MA value increased（P < 0.01）. The K value of patients with mild pelvic adhesions was higher than those with moderate and severe pelvic adhesions，but the α Angle and MA values were lower，the differences were statistically significant（P < 0.05）. The α Angle and MA values of patients without or partially closed uterine rectum depression were lower than those of patients with com⁃ plete rectum depression，the α Angle，MA and CI values of patients with cysts less than or equal to 5 cm were lower than those of patients with cysts more than 5 cm（P < 0.01）. No significant difference was noted in TEG index between patients with and without dysmenorrhea. Conclusion The changes of TEG indicators were closely related to the occurrence and development of EMs，which could be used as one of the indicators to predict the occurrence and development of EMs. The detection of TEG in patients was helpful for early diagnosis and prognosis discrimina⁃ tion，and provided reference for the evaluation of patients′ condition，the prediction of surgical difficulty and the formulation of treatment plan.

Key words:

endometriosis, coagulation, thromboelastograph, benign ovarian tumor