实用医学杂志 ›› 2022, Vol. 38 ›› Issue (10): 1251-1254.doi: 10.3969/j.issn.1006⁃5725.2022.10.015

• 临床研究 • 上一篇    下一篇

经皮神经电刺激联合加速康复外科多模式镇痛在腹腔镜全子宫切除术后的镇痛效果

韦玮 方梓羽 马艳群 张春兰 陈萍 吴伟英    

  1. 广西医科大学第四附属医院(柳州市工人医院)妇产科(广西柳州 545005)

  • 出版日期:2022-05-25 发布日期:2022-05-25
  • 通讯作者: 吴伟英 E⁃mail:2160844915@qq.com
  • 基金资助:
    广西壮族自治区卫生健康委员会自筹经费科研课题(编号:Z20191092)

Analysis of analgesic effect of TENS combined with ERAS multi ⁃mode analgesia after laparoscopic total hysterectomy

WEI Wei,FANG Ziyu,MA Yanqun,ZHANG Chunlan,CHEN Ping,WU Weiying.   

  1. Department of Obstetrics and Gynecology,the Fourth Affiliated Hospital of Guangxi Medical University,Liuzhou Workers′ Hospital Liuzhou 545005,China

  • Online:2022-05-25 Published:2022-05-25
  • Contact: WU Weiying E⁃mail:2160844915@qq.com

摘要:

目的 探讨经皮神经电刺激(TENS)联合加速康复外科(ERAS)多模式镇痛在腹腔镜全子宫 切除术后的镇痛效果。方法 选取拟行腹腔镜全子宫切除术患者60例,随机分为ERAS组和ERAS + TENS 组,每组30例。比较两组患者术后4、8、16、24 h疼痛程度视觉模拟评分(VAS)和Ramsay镇静评分。于患者麻醉诱导前、手术开始 30 min、术后清醒时检测血清 β⁃内啡肽水平。比较两组患者术中出血量、手术时 间、术中麻醉药物用量、术后48 h恶心呕吐发生率、术后排气时间、术后住院时间。结果 与ERAS组相比, ERAS + TENS 组术后 16 h 内疼痛 VAS 评分下降,术后 8 h 16 h Ramsay 镇静评分较升高(P < 0.05)。手 术开始 30 min 和术后清醒时,ERAS+TENS β⁃内啡肽水平较 ERAS 组明显升高(P < 0.05)。两组患者术 中出血量、手术时间、术后住院时间、术后排气时间、术中异丙酚和瑞芬太尼用量、恶心呕吐发生率比较差 异均无统计学意义(P > 0.05),但 ERAS+TENS 组非切口痛发生率明显下降(P < 0.05)。结论 TENS 联合 ERAS 多模式镇痛可降低腹腔镜全子宫切除术患者术后的疼痛感,提高镇静舒适度,但无法减少阿片类药 物用量。

关键词:

子宫肌瘤, 经皮神经电刺激, 加速康复外科, 腹腔镜全子宫切除术, 镇痛

Abstract:

Objective To investigate the analgesic effect of multi⁃mode percutaneous electrical nerve stim⁃ ulation(TENS)combined with multi ⁃mode analgesia of enhanced recovery after surgery(ERAS)in laparoscopic total hysterectomy. Methods Sixty patients who planned to undergo laparoscopic total hysterectomy were randomly divided into ERAS group(n=30)and ERAS + TENS group(n = 30). Visual analogue scale(VAS)and Ramsay sedation score were compared between two groups at 4 h,8 h,16 h and 24 h after surgery. Serum β⁃endorphin lev⁃ els were detected before anesthesia induction,30 min after operation,and when patients were awake after surgery. The amount of intraoperative blood loss,operation time,intraoperative anesthetic dosage,nausea and vomiting in postoperative 48 h,postoperative exhaust time and postoperative hospital stay were compared between the two groups. Results Compared with ERAS group,the VAS score decreased at 16 h after surgery,and Ramsay seda⁃ tion score increased at 8 h and 16 h after surgery in ERAS+TENS group(P < 0.05). The levels of β⁃endorphin in ERAS+TENS group were significantly higher than those in ERAS+TENS group at 30 min after operation and at post⁃ operative wakefulness(P < 0.05). There were no significant differences in intraoperative blood loss,operation du⁃ ration,postoperative hospital stay,postoperative exhaust time,dosage of propofol and remifentanil,and incidence of nausea and vomiting between the two groups(P > 0.05). But the incidence of non⁃incision pain was significantly decreased in ERAS + TENS group(P < 0.05). Conclusion TENS combined with ERAS multi ⁃mode analgesia could reduce postoperative pain and improve sedation comfort in patients with laparoscopic total hysterectomy,but could not reduce the amount of opioids.

Key words:

fibroid, transcutaneous electrical nerve stimulation, enhanced recovery after surgery, laparoscopic total hysterectomy, analgesia